血清和尿液白细胞介素17（IL-17）对膀胱癌预测诊断的临床研究
Clinical Study on the Predictive Diagnosis of Bladder Cancer by Serum and Urine Interleukin - 17 (IL - 17)
提交：2024-04-22修改：2024-05-16录用：2024-07-15出版：2024-08-20
环球医学进展, 2024, 3(1), 37-41
课题资助：江西省卫生健康委科技计划项目（202312248）
摘要：探讨血液和尿液白细胞介素17（IL-17）的表达水平对膀胱癌预测的影响。本研究人群为2022年3月至2023年10月在我院诊断的膀胱癌患者纳入为实验组，以我院同时期体检的健康人群纳入为对照组。比较两组患者的血液和尿液IL-17水平进行分析。共纳入实验组患者31例，健康对照组34例。实验组患者的血液和尿液的IL-17均高于健康对照组，差异具有统计学意义（均＜0.05）。此外，当检测血清和尿液【更多...】
关键词：白介素-17；膀胱癌；标记物；疾病进展
关键词： 白介素-17；膀胱癌；标记物；疾病进展
摘要
摘 要：
探讨血液和尿液白细胞介素17（IL-17）的表达水平对膀胱癌预测的影响。本研究人群为2022年3月至2023年10月在我院诊断的膀胱癌患者纳入为实验组，以我院同时期体检的健康人群纳入为对照组。比较两组患者的血液和尿液IL-17水平进行分析。共纳入实验组患者31例，健康对照组34例。实验组患者的血液和尿液的IL-17均高于健康对照组，差异具有统计学意义（均＜0.05）。此外，当检测血清和尿液样本之间的差异时，发现血清中的差异明显更高。白介素-17是预测膀胱癌疾病发生和进展有效的免疫标记物。
探讨血液和尿液白细胞介素17（IL-17）的表达水平对膀胱癌预测的影响。本研究人群为2022年3月至2023年10月在我院诊断的膀胱癌患者纳入为实验组，以我院同时期体检的健康人群纳入为对照组。比较两组患者的血液和尿液IL-17水平进行分析。共纳入实验组患者31例，健康对照组34例。实验组患者的血液和尿液的IL-17均高于健康对照组，差异具有统计学意义（均＜0.05）。此外，当检测血清和尿液样本之间的差异时，发现血清中的差异明显更高。白介素-17是预测膀胱癌疾病发生和进展有效的免疫标记物。
关键词：白介素-17；膀胱癌；标记物；疾病进展
Abstract:
Objective: To explore the impact of the expression levels of interleukin-17 (IL-17) in blood and urine on the prediction of bladder cancer. Methods: The study population consisted of bladder cancer patients diagnosed at our hospital between March 2022 and October 2023, included as the experimental group, and a healthy control group consisting of individuals undergoing physical examinations during the same period. The blood and urine IL-17 levels between the two groups were compared and analyzed. Results: A total of 31 patients were included in the experimental group and 34 in the control group. The blood and urine IL-17 levels in the experimental group were both significantly higher than those in the control group ( < 0.05 for both). Additionally, a higher difference in IL-17 levels was observed in serum compared to urine samples. Conclusion: Interleukin-17 is an effective immunomarker for predicting the occurrence and progression of bladder cancer.
Objective: To explore the impact of the expression levels of interleukin-17 (IL-17) in blood and urine on the prediction of bladder cancer. Methods: The study population consisted of bladder cancer patients diagnosed at our hospital between March 2022 and October 2023, included as the experimental group, and a healthy control group consisting of individuals undergoing physical examinations during the same period. The blood and urine IL-17 levels between the two groups were compared and analyzed. Results: A total of 31 patients were included in the experimental group and 34 in the control group. The blood and urine IL-17 levels in the experimental group were both significantly higher than those in the control group ( < 0.05 for both). Additionally, a higher difference in IL-17 levels was observed in serum compared to urine samples. Conclusion: Interleukin-17 is an effective immunomarker for predicting the occurrence and progression of bladder cancer.
Keywords: Interleukin-17; Bladder cancer; Biomarker; Disease progression
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